Australian actor and martial artist Richard Norton died in 2025 due to heart failure linked to unapproved peptide treatments. A coroner has called for the Therapeutic Goods Administration to review unapproved peptides following his death. The incident has raised concerns about the safety of unapproved peptides. The death may be the first confirmed fatality linked to unapproved peptides. The coroner's report highlights the need for further investigation into the safety of unapproved peptides.